COSMIC is a comprehensive global resource for information on somatic mutations in human cancer, combining curation of the scientific literature with tumor resequencing data from the Cancer Genome Project at the Sanger Institute, U.K. This collection references genes.

This resource is a provider. This means that while it may have its own prefix, it actually reuses the identifiers provided by the hgnc.symbol prefix. For all use cases, you should use hgnc.symbol instead of cosmic.gene.

Prefix

cosmic.gene

Alternative Prefixes

cosmic

Keywords

biomedical science genetics

Links

Homepage

Contact

John G Tate   0000-0002-8315-6574   jgtate

Pattern for Local Unique Identifiers

Local identifiers in COSMIC Gene should match this regular expression:
^[A-Z0-9][A-Z0-9-]*$

Example Local Unique Identifier

BRAF   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from COSMIC Gene should match this regular expression:
^cosmic\.gene:[A-Z0-9][A-Z0-9-]*$

Example CURIE

cosmic.gene:BRAF

Publications

• 2019 COSMIC: the Catalogue Of Somatic Mutations In Cancer
• 2014 COSMIC: exploring the world's knowledge of somatic mutations in human cancer
• 2010 COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
• 2004 The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website

A summary of the relations in the Semantic Farm schema can be found here.

Provides

hgnc.symbol

In Collection

FHIR External Terminologies Synapse.org external links

The metaregistry provides mappings between the Semantic Farm and other registries. There are 5 mappings to external registries for this resource with 3 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier BRAF is used to demonstrate the providers available for COSMIC Gene. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.