This controlled vocabulary contains terms to describe the mechanism of action for a chemical-target interaction. The terms can be retrieved from ACTION_TYPE table in ChEMBL's SQL dump and are used to annotate the DRUG_MECHANISM table. Because these aren't really identifiers, they are transformed by lowercasing and replacing spaces with dashes to form 'identifiers'. The pattern in the Bioregistry record contains an enumeration of the 33 allowed values as of ChEMBL v35.
- Prefix
chembl.mechanism- License
- CC-BY-SA-3.0
- Links
- Homepage Mailing List
- Contact
- David Mendez Lopez 0000-0002-0294-5484 nclopezo
- Pattern for Local Unique Identifiers
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Local identifiers in ChEMBL mechanism should match this regular expression:
^activator|agonist|allosteric-antagonist|antagonist|antisense-inhibitor|binding-agent|blocker|chelating-agent|cross-linking-agent|degrader|disrupting-agent|exogenous-gene|exogenous-protein|hydrolytic-enzyme|inhibitor|inverse-agonist|methylating-agent|modulator|negative-allosteric-modulator|negative-modulator|opener|other|oxidative-enzyme|partial-agonist|positive-allosteric-modulator|positive-modulator|proteolytic-enzyme|reducing-agent|releasing-agent|rnai-inhibitor|sequestering-agent|stabiliser|substrate|vaccine-antigen$ - Example Local Unique Identifiers
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activator
cross-linking-agent
negative-allosteric-modulator - Pattern for CURIES
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Compact URIs (CURIEs) constructed from ChEMBL mechanism should match this regular expression:
^chembl\.mechanism:activator|agonist|allosteric-antagonist|antagonist|antisense-inhibitor|binding-agent|blocker|chelating-agent|cross-linking-agent|degrader|disrupting-agent|exogenous-gene|exogenous-protein|hydrolytic-enzyme|inhibitor|inverse-agonist|methylating-agent|modulator|negative-allosteric-modulator|negative-modulator|opener|other|oxidative-enzyme|partial-agonist|positive-allosteric-modulator|positive-modulator|proteolytic-enzyme|reducing-agent|releasing-agent|rnai-inhibitor|sequestering-agent|stabiliser|substrate|vaccine-antigen$ - Example CURIEs
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chembl.mechanism:activator
chembl.mechanism:cross-linking-agent
chembl.mechanism:negative-allosteric-modulator - Contributors
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- submitter Charles Tapley Hoyt 0000-0003-4423-4370 cthoyt
Providers
A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).
This resource does not have any providers. Please consider contributing one after reading the curation guide.