appears_in: []
contact:
  email: dmendez@ebi.ac.uk
  github: nclopezo
  name: David Mendez Lopez
  orcid: 0000-0002-0294-5484
contributor:
  email: cthoyt@gmail.com
  github: cthoyt
  name: Charles Tapley Hoyt
  orcid: 0000-0003-4423-4370
depends_on: []
deprecated: false
description: This controlled vocabulary contains terms to describe the mechanism of
  action for a chemical-target interaction. The terms can be retrieved from ACTION_TYPE
  table in ChEMBL's SQL dump and are used to annotate the DRUG_MECHANISM table. Because
  these aren't really identifiers, they are transformed by lowercasing and replacing
  spaces with dashes to form 'identifiers'. The pattern in the Bioregistry record
  contains an enumeration of the 33 allowed values as of ChEMBL v35.
example: activator
example_extras:
- cross-linking-agent
- negative-allosteric-modulator
homepage: https://www.ebi.ac.uk/chembl
keywords: []
license: CC-BY-SA-3.0
logo: https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg5LCdi4mEW56jpmM0YDjEwLtGUUy2F9I7m02I9hygI0OPugnZKlTrAgfBtug5yJS5RbpCXifID0pzA5Wxdc6un1UjCCtOJcvlkeoAFgzQspvplZcstYNwx8lBtvlYY8WJ-kLj-I891VIAO/s1600/Screenshot+2018-12-20+at+10.30.09.png
mappings: {}
name: ChEMBL mechanism
namespace_in_lui: false
owners:
- name: European Bioinformatics Institute
  ror: 02catss52
part_of: chembl
pattern: ^activator|agonist|allosteric-antagonist|antagonist|antisense-inhibitor|binding-agent|blocker|chelating-agent|cross-linking-agent|degrader|disrupting-agent|exogenous-gene|exogenous-protein|hydrolytic-enzyme|inhibitor|inverse-agonist|methylating-agent|modulator|negative-allosteric-modulator|negative-modulator|opener|other|oxidative-enzyme|partial-agonist|positive-allosteric-modulator|positive-modulator|proteolytic-enzyme|reducing-agent|releasing-agent|rnai-inhibitor|sequestering-agent|stabiliser|substrate|vaccine-antigen$
preferred_prefix: chembl.mechanism
prefix: chembl.mechanism
providers: []
publications: []
synonyms: []
