TopFIND is a database of protein termini, terminus modifications and their proteolytic processing in the species: Homo sapiens, Mus musculus, Arabidopsis thaliana, Saccharomyces cerevisiae and Escherichia coli.

This resource is a provider. This means that while it may have its own prefix, it actually reuses the identifiers provided by the uniprot prefix. For all use cases, you should use uniprot instead of topfind.

Prefix

topfind

Keywords

alternative mrna splicing, via spliceosome annotation c-terminal amino-acid residue evidence life science molecular interaction n-terminal amino-acid residue polypeptide region protease cleavage protease site protein binding protein domain protein modification process proteolytic digest sequence annotation translational initiation

Links

Homepage

Publications

2014 Proteome TopFIND 3.0 with TopFINDer and PathFINDer: database and analysis tools for the association of protein termini to pre- and post-translational events

2011 TopFIND 2.0--linking protein termini with proteolytic processing and modifications altering protein function

2011 TopFIND, a knowledgebase linking protein termini with function

Pattern for Local Unique Identifiers

Local unique identifiers in TopFind should match this regular expression:
^([A-N,R-Z][0-9][A-Z][A-Z, 0-9][A-Z, 0-9][0-9])|([O,P,Q][0-9][A-Z, 0-9][A-Z, 0-9][A-Z, 0-9][0-9])$

Example Local Unique Identifier

Q9UKQ2   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from TopFind should match this regular expression:
^topfind:([A-N,R-Z][0-9][A-Z][A-Z, 0-9][A-Z, 0-9][0-9])|([O,P,Q][0-9][A-Z, 0-9][A-Z, 0-9][A-Z, 0-9][0-9])$

Example CURIE

topfind:Q9UKQ2

Contact

Christopher M. Overall   0000-0001-5844-2731

A summary of the relations in the Semantic Farm schema can be found here.

Provides

uniprot

Mappings from records in Semantic Farm to external registries comprises the metaregistry. This resource has 5 mappings to external registries with 3 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier Q9UKQ2 is used to demonstrate the providers available for TopFind. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.