The PANTHER (Protein ANalysis THrough Evolutionary Relationships) Classification System is a resource that classifies genes by their functions, using published scientific experimental evidence and evolutionary relationships to predict function even in the absence of direct experimental evidence. This collection references groups of genes that have been organised as families.

Prefix

panther.family

Keywords

classification family and domain databases gene ontology pathway protein

License

http://www.pantherdb.org/tou.jsp

Links

Homepage

Publications

https://bioregistry.io/pubmed:33290554

2019 PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

2003 PANTHER: a library of protein families and subfamilies indexed by function

Pattern for Local Unique Identifiers

Local identifiers in PANTHER Family should match this regular expression:
^PTHR\d{5}(\:SF\d{1,3})?$

Example Local Unique Identifier

PTHR12345   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from PANTHER Family should match this regular expression:
^panther\.family:PTHR\d{5}(\:SF\d{1,3})?$

Example CURIE

panther.family:PTHR12345

Contact

Paul D Thomas   0000-0002-9074-3507

Identifier Space Owner

Keck School of Medicine, University of Southern California

A summary of the relations in the Semantic Farm schema can be found here.

In Collection (2)

Global Biodata Coalition - Global Core Biodata Resources Synapse.org external links

Mappings from records in Semantic Farm to external registries comprises the metaregistry. This resource has 7 mappings to external registries with 3 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier PTHR12345 is used to demonstrate the providers available for PANTHER Family. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.

Additional providers curated in the Semantic Farm are listed here. These are typically inherited from Identifiers.org or Prefix Commons, and need extra curation.