The G protein-coupled receptor database (GPCRDB) collects, large amounts of heterogeneous data on GPCRs. It contains experimental data on sequences, ligand-binding constants, mutations and oligomers, and derived data such as multiple sequence alignments and homology models.

Prefix

gpcrdb

Keywords

3d structure bioactive entity drug homologous life science molecular biology mutation orthologous protein protein family/group databases protein structure sequence sequence alignment small molecule snp structure-based sequence alignment

Links

Homepage

Publications

1998 GPCRDB: an information system for G protein-coupled receptors

2024 GPCRdb in 2025: adding odorant receptors, data mapper, structure similarity search and models of physiological ligand complexes

2022 GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources

2021 GPCRdb in 2021: integrating GPCR sequence, structure and function

2018 GPCRdb in 2018: adding GPCR structure models and ligands

2016 GPCRdb: the G protein-coupled receptor database - an introduction

2015 GPCRdb: an information system for G protein-coupled receptors

2013 GPCRDB: an information system for G protein-coupled receptors

2010 GPCRDB: information system for G protein-coupled receptors

2003 GPCRDB information system for G protein-coupled receptors

2001 Collecting and harvesting biological data: the GPCRDB and NucleaRDB information systems

Pattern for Local Unique Identifiers

Local unique identifiers in G protein-coupled receptor database should match this regular expression:
^\w+$

Example Local Unique Identifier

RL3R1_HUMAN   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from G protein-coupled receptor database should match this regular expression:
^gpcrdb:\w+$

Example CURIE

gpcrdb:RL3R1_HUMAN

Contact

David Gloriam   0000-0002-4299-7561

Identifier Space Owner

Radboud University Nijmegen Medical Centre, Nijmegen

Mappings from records in Semantic Farm to external registries comprises the metaregistry. This resource has 7 mappings to external registries with 4 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier RL3R1_HUMAN is used to demonstrate the providers available for G protein-coupled receptor database. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.

Additional providers curated in the Semantic Farm are listed here. These are typically inherited from Identifiers.org or Prefix Commons, and need extra curation.