CMEO (Clinical Metadata Exploration Ontology) is an ontology for representing and querying study- and variable-level metadata from clinical cohort studies in a consistent, machine-interpretable way. CMEO models the semantics of data elements (variables) and their key metadata needed for cross-cohort discovery and harmonization - such as human-readable labels/definitions, domain/type information (e.g., condition, measurement, medication), permissible categorical values, units, visit/timepoint context, derivation/provenance (e.g., computed variables), and basic descriptive statistics. It is designed to support metadata-driven tasks including cohort cataloguing, feasibility assessment, study retrieval, and identification of compatible variables across studies - without requiring access to patient-level data. CMEO is intended to interoperate with controlled vocabularies and common clinical terminologies by linking data elements and value sets to external concept identifiers (e.g., OMOP concept IDs, SNOMED CT, LOINC, RxNorm/ATC, UCUM) while remaining model-agnostic (i.e., not tied to a single CDM).

Prefix
cmeo
Preferred Prefix
CMEO
Keywords
ontology
License
CC-BY-4.0
Links
Homepage Repository OWL
Publications
CMEO: a metadata-centric ontology for clinical studies exploration and harmonization assessment
Identifier Standards
Pattern for Local Unique Identifiers
Missing LUI pattern
Example Local Unique Identifier
0000009   Resolve
Example CURIE
CMEO:0000009
Format String for RDF URIs
http://purl.obolibrary.org/obo/CMEO_$1
Example RDF URI
http://purl.obolibrary.org/obo/CMEO_0000009
Mappings to External Registries

Mappings from records in Semantic Farm to external registries comprises the metaregistry. This resource has 2 mappings to external registries with 1 unique external prefixes.

Registry Name Registry Metaprefix External Prefix Curate
OBO Foundry ontology obofoundry cmeo
OLS EBI Ontology Lookup Service logo ols cmeo
Providers

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 0000009 is used to demonstrate the providers available for Clinical Metadata Exploration Ontology. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.

Provider Name Provider Code URI
Clinical Metadata Exploration Ontology (RDF) rdf http://purl.obolibrary.org/obo/CMEO_0000009
Bioregistry bioregistry https://bioregistry.io/cmeo:0000009
OBO Foundry ontology obofoundry http://purl.obolibrary.org/obo/CMEO_0000009
EBI Ontology Lookup Service ols https://www.ebi.ac.uk/ols/ontologies/cmeo/terms?iri=http://purl.obolibrary.org/obo/CMEO_0000009