A CIViC Gene Summary is created to provide a high-level overview of clinical relevance of cancer variants for the gene. Gene Summaries in CIViC focus on emphasizing the clinical relevance from a molecular perspective rather than describing the biological function of the gene unless necessary to contextualize its clinical relevance in cancer. Gene Summaries include relevant cancer subtypes, specific treatments for the gene’s associated variants, pathway interactions, functional alterations caused by the variants in the gene, and normal/abnormal functions of the gene with associated roles in oncogenesis

Prefix

civic.gid

Alternative Prefixes

civic.gene

Keywords

gene ontology

License

CC0-1.0

Links

Homepage OBO OWL OBO JSON

Pattern for Local Unique Identifiers

Local identifiers in CIViC gene should match this regular expression:
^[0-9]+$

Example Local Unique Identifier

272   Resolve

Pattern for CURIES

Compact URIs (CURIEs) constructed from CIViC gene should match this regular expression:
^civic\.gid:[0-9]+$

Example CURIE

civic.gid:272

Contact

Malachi Griffith   0000-0002-6388-446X   malachig

Group Contact

Mailing List

Identifier Space Owner

Washington University in St. Louis

A summary of the relations in the Semantic Farm schema can be found here.

In Collection (2)

Global Biodata Coalition - Global Core Biodata Resources Synapse.org external links

Mappings from records in Semantic Farm to external registries comprises the metaregistry. This resource has 2 mappings to external registries with 2 unique external prefixes.

A provider turns a local unique identifiers from a resource into a URI. Many providers are also resolvable as URLs (i.e., they can be used in a web browser).

The local unique identifier 272 is used to demonstrate the providers available for CIViC gene. Some providers may use a different example, which is displayed in the table below. A guide for curating additional providers can be found here.