appears_in: []
contact:
  email: c.orengo@ucl.ac.uk
  name: Christine Orengo
  orcid: 0000-0002-7141-8936
depends_on: []
deprecated: false
description: CATH is a classification of protein structural domains. We group protein
  domains into superfamilies when there is sufficient evidence they have diverged
  from a common ancestor. CATH can be used to predict structural and functional information
  directly from protein sequence.
example: 1.10.8.10
example_extras: []
homepage: http://www.cathdb.info
keywords:
- 3d structure
- classification
- protein
- sequence
- structure
mappings:
  biocontext: CATH
  edam: '2700'
  integbio: nbdc01888
  miriam: cath
  n2t: cath
  prefixcommons: cath
  re3data: r3d100012629
name: CATH Protein Structural Domain Superfamily
namespace_in_lui: false
owners:
- name: University College London
  ror: 02jx3x895
pattern: ^[1-6]\.[0-9]+\.[0-9]+\.[0-9]+$
preferred_prefix: cath
prefix: cath
providers:
- code: bio2rdf
  description: Bio2RDF is an open-source project that uses Semantic Web technologies
    to build and provide the largest network of Linked Data for the Life Sciences.
    Bio2RDF defines a set of simple conventions to create RDF(S) compatible Linked
    Data from a diverse set of heterogeneously formatted sources obtained from multiple
    data providers.
  homepage: https://bio2rdf.org
  name: Bio2RDF
  uri_format: http://bio2rdf.org/cath:$1
publications:
- doi: 10.1016/s0969-2126(97)00260-8
  pubmed: '9309224'
  title: CATH--a hierarchic classification of protein domain structures
  year: 1997
- doi: 10.1093/nar/gkae1087
  pubmed: '39565206'
  title: 'CATH v4.4: major expansion of CATH by experimental and predicted structural
    data'
  year: 2024
- doi: 10.1093/nar/gkaa1079
  pmc: PMC7778904
  pubmed: '33237325'
  title: 'CATH: increased structural coverage of functional space'
  year: 2021
- doi: 10.1093/nar/gky1097
  pmc: PMC6323983
  pubmed: '30398663'
  title: 'CATH: expanding the horizons of structure-based functional annotations for
    genome sequences'
  year: 2019
- doi: 10.1093/nar/gkx1069
  pmc: PMC5753370
  pubmed: '29112716'
  title: 'Gene3D: Extensive prediction of globular domains in proteins'
  year: 2018
- doi: 10.1093/nar/gkw1098
  pmc: PMC5210570
  pubmed: '27899584'
  title: 'CATH: an expanded resource to predict protein function through structure
    and sequence'
  year: 2016
- doi: 10.1093/bioinformatics/btw473
  pmc: PMC5018379
  pubmed: '27477482'
  title: 'Functional classification of CATH superfamilies: a domain-based approach
    for protein function annotation'
  year: 2016
- doi: 10.1016/j.biochi.2015.08.004
  pmc: PMC4678953
  pubmed: '26253692'
  title: The history of the CATH structural classification of protein domains
  year: 2015
- doi: 10.1093/nar/gku947
  pmc: PMC4384018
  pubmed: '25348408'
  title: 'CATH: comprehensive structural and functional annotations for genome sequences'
  year: 2014
- pubmed: '11788987'
  title: 'The CATH protein family database: a resource for structural and functional
    annotation of genomes'
  year: 2002
synonyms: []
uri_format: http://www.cathdb.info/cathnode/$1
